Why genome editing technologies

HRB focuses on developing platform technologies that enable CRISPR-based genome editing and applying these towards genetic crop optimization for improved yields, disease resistance and nutritional value. Genome editing is allowing us to rethink our approach to serious challenges in agriculture, food and pharma. We now have the ability to precisely edit the DNA of a living plant, opening up the possibility of correcting and optimizing genetic material at its source. These efforts ultimately contribute to solving global challenges such as the need for improved yields and nutritional value, or reduced pesticide use. This is how we create a more sustainable future.

Why Hudson River Biotechnology

We employ the latest genetic technology and state-of-art science to optimize plants. HRB can be your co-development partner for all aspects of genome editing projects, as our platforms offer the full spectrum of technologies needed. For partners who already have substantial in-house capabilities, HRB can supplement by providing proprietary solutions to specific parts of the work flow (for example, enhancing transfection capabilities, developing crop-specific applications). For other partners, we can provide a complete end-to-end solution, from concept to a modified crop ready for field or greenhouse testing. This includes technical aspects such as target identification, CRISPR guide design and validation, transfection and plant regeneration, as well as commercial aspects such as navigating the regulatory environment and intellectual property landscape.

How to work with HRB

We enable companies of all sizes – from seed companies, ingredient producers or buyers to other biotech firms – to create tomorrows crops with today’s technology. HRB can act as a technology provider, contributing specific technological solutions to companies with already existing genomic capabilities; or, as a complete end-to-end solution for partners with breeding needs.

Seed companies

Seed companies with already existing genomic capabilities often face specific technological barriers with gene editing such as unique target discovery, transfection efficiency, guide design and difficulties in regeneration. HRB has, or is developing, solutions to all of these problems and can act as a technology provider or trait development partner. Either through breeding projects, technological co-development or licensing, HRB brings the solutions you need.

Food and ingredient companies

Gene editing opens up a whole new range of possibilities to food and ingredient companies. HRB has the in-house R&D capabilities to create completely new varieties that will amaze consumers with healthier and more nutritious products. We look forward to partner with you. Get in touch with us today!

CRISPR in the EU

For the time being, CRISPR-edited plant crops are considered GMOs and as such essentially barred from entering the market. However, even for EU applications CRISPR has tremendous value as an accelerator of conventional breeding technologies. For example, we can identify targets and confirm these via CRISPR, after which we genetically screen through a large population of randomly mutagenized plants to identify similar mutants. This results in new varieties that are fully compliant with EU regulations. For more details, including how CRISPR can be applied in your geographical area(s) of interest, please contact us.

Our facilities

HRB’s laboratory facilities are located in the Wageningen BioPartner center and are fully equipped for our activities related to DNA, RNA, protein purification and plant transformation. In addition HRB maintains an official collaboration with nearby Wageningen University and several other academic research institutions, providing us access to their extensive research infrastructure, and to the latest insights in the field.